Was Adam (of Adam and Eve fame) patient zero in the male loneliness epidemic? In this episode, the ladies chat about social isolation and welcome their first guest, Producer Paul, to introduce some y-chromies and testosterone into the mix. We focus on the medicalization of loneliness, friend tech, and other budding business solutions to commodify connection. Your loss is their [capital] gain.

SOURCES

https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf

https://www.belonginstitute.com/courses/2025-in-person-community-building-intensive-2

https://www.statista.com/topics/11644/loneliness-in-the-us/

https://www.scienceofpeople.com/loneliness-statistics/

https://abcnews.go.com/Health/500-cases-measles-reported-nationwide-19-states-cdc/story?id=120251851

https://fortune.com/2025/03/28/23andme-bankruptcy-chapter-11-genetic-data-medical-ancestry-dna-silicon-valley-delete/

https://www.cbsnews.com/news/colorado-psychedelic-mushrooms-healing-centers/

https://www.jnj.com/media-center/press-releases/u-s-fda-approves-tremfya-guselkumab-the-first-and-only-il-23-inhibitor-offering-both-subcutaneous-and-intravenous-induction-options-for-adult-patients-with-moderately-to-severely-active-crohns-disease

In this week’s episode, we bring you a dispatch from AHAIC 2025 (Africa Health Agenda International Conference), take control of the bro-centric longevity conversation, and look into what the girligarchs are up to in the femtech space. What are the market opportunities in this billion-dollar industry? Who’s funding it? Will it impact our well-being or is this just a pink-washed cash grab? And why did it take so long to realize women are not just small men?

LINKS + SOURCES

Investment in health: www.weforum.org/stories/2023/01/davos2023-womens-health-rethinking-the-cost-as-an-investment-for-societal-gain

Gender gap in medical research: https://time.com/7171341/gender-gap-medical-research/ 

Antidepressant gender differences: https://pmc.ncbi.nlm.nih.gov/articles/PMC5286730/#:~:text=Factors%20that%20may%20contribute%20to%20sex%20differences%20in%20antidepressant%20efficacy.&text=A%20number%20of%20studies%20suggest,these%20studies%20has%20been%20disputed.

Women Spending Power: https://nielseniq.com/global/en/insights/analysis/2024/shaping-success-a-deep-dive-into-womens-impact-on-the-cpg-landscape/ 

FemTech Market: https://www.grandviewresearch.com/industry-analysis/femtech-market-report

Menopause Market: https://www.managedhealthcareexecutive.com/view/international-menopause-market-expected-to-reach-27-63-billion-by-2033 

VO2 max + longevity: https://www.jacc.org/doi/10.1016/j.jacc.2018.06.045

Society has moved past the bootstrap girlboss era. We’re obsessed with sleepmaxxing and the business world has noticed. This week’s episode is all about R&R—no, not that kind. Re$$$t & Revenue. We start with a brief weather report on tech CEO ketamine slumber parties, RFK Jr. confirmation, and pharma drama, then discuss all things sleep. Cozy up and press play.

RESOURCES & REFERENCES

Weather Report

• Don’t Die Summit: https://fortune.com/well/article/bryan-johnson-tech-millionaire-dont-die-summit/

• Ketamine Slumber Parties: https://www.wired.com/story/ketamine-psychedelic-slumber-parties-tech-executives/ 

• MAHA Exec Order: https://www.whitehouse.gov/presidential-actions/2025/02/establishing-the-presidents-make-america-healthy-again-commission/

• Jury still out on glyphosate: https://www.nytimes.com/2025/02/19/well/glyphosate-health-cancer.html

• Trump Admin Bird Flu Blunder: https://www.nbcnews.com/politics/white-house/trumps-drive-reshape-government-threaten-bird-flu-response-rcna192133 

• Treating ADHD Lifespan: https://www.cnn.com/2024/03/12/health/adhd-medication-lower-risk-of-death-study/index.html 

Sleep Deep-Dive

• Business of sleep: https://www.axios.com/2024/01/13/sleep-tech-supplements-bedding-healthy

• Defining Sleepmaxxing: https://dailyconcept.substack.com/p/what-is-sleepmaxxing?utm_source=%2Fsearch%2Fsleep%2520hygiene&utm_medium=reader2

• Getting good sleep could add years to your life: https://www.acc.org/About-ACC/Press-Releases/2023/02/22/21/35/Getting-Good-Sleep-Could-Add-Years-to-Your-Life 

• Quality of Melatonin and CBD Gummies in US: https://jamanetwork.com/journals/jama/fullarticle/2804077

• Gallup Americans sleep less: https://news.gallup.com/poll/642704/americans-sleeping-less-stressed.aspx

• 40% of employees in a 4-day workweek trial reported fewer sleep issues: https://www.businessinsider.com/4-day-work-week-employees-report-decrease-insomnia-sleep-problems-2023-2#:~:text=40%25%20of%20the%20around%202%2C900,an%20increase%20in%20sleep%20issues. 

• Veteran Study: https://www.sciencedirect.com/science/article/abs/pii/S016503272101209X 

• Cost of Productivity, Obstructive Sleep Apnea: https://med.umn.edu/news/obstructive-sleep-apnea-hidden-health-crisis-america#:~:text=A%20recent%20study%20by%20the,%2C%20physical%2C%20and%20economic%20benefits 

• Zepbound FDA approved for sleep apnea: https://www.fda.gov/news-events/press-announcements/fda-approves-first-medication-obstructive-sleep-apnea 

• Sleep Trends: https://globalwellnessinstitute.org/global-wellness-institute-blog/2024/04/30/sleep-initiative-trends-for-2024/ 

On the first episode, we dive into the booming world of longevity clinics.  What do they offer?  What’s the hype?  And why are Gen Z/millennials dropping serious cash on anti-aging?  We look into the rise (and fall!) of spots like Extension Health, Hooke, Modern Age, and Forward, the recent TikTok drama around Continuum, and what the broligarchs (think: Sam Altman, Jeff Bezos) are backing.  We also learn that Emily is bullish on hyperbaric oxygen tanks and that brain rot might be…fake news.  Is longevity the future?  Listen to find out. Resources and References:

• The Global Wellness Industry Is Now Worth $6.3 Trillion: https://archive.is/ydXjm

•  Article about Longevity Written in the Atlantic in 1928: https://www.theatlantic.com/magazine/archive/1928/05/the-secret-of-longevity/649408/

Defining what a longevity clinic actually is:

• The Longevity Clinic Will See You Now—for $100,000: https://www.wsj.com/health/longevity-clinics-aging-living-longer-2b98e773

• Modern Age has closed: https://beautymatter.com/articles/nyc-based-longevity-clinic-modern-age-to-close

F45 now also has GLP1s: https://insider.fitt.co/issue-no-282-gym-as-clinic/

Neko Health, the body-scanning AI health startup from Spotify’s Daniel Ek, opens in London: https://www.nekohealth.com/se/en/neko-health-raises-260m-series-b